Standardization of a recipe based on the roots of Carica papaya and the leaves of Alchornea cordifolia traditionally used for its healing properties

Title : Standardization of a recipe based on the roots of Carica papaya and the leaves of Alchornea cordifolia traditionally used for its healing properties

Abstract:

Introduction: In order to promote traditional medicine, we have standardized a recipe based on the roots of Carica papaya and the leaves of Alchornea cordifolia traditionally used for its healing properties. This process went through ethnobotanical, phytochemical and pharmacological standardization.
Methodology: This was an experimental study which took place from November 25, 2023 to May 31, 2024. The ethnobotanical survey was done with a traditional health practitioner in Yaoundé, and 02 plants were identified at National Herbarium. A healing recipe obtained served as a basis for producing the monographs, after qualitative and quantitative phytochemical screening. Then antioxidant pharmacological activity in vitro were done. 
Results: Monographs drawn up revealed presence of starch granules, suber, epidermal cells, fibers and palisade tissues. The phytochemical screening showed presence of polyphenols, flavonoids, mucilages, saponosides, tannins, cardiac glycosides, carbohydrates, proteins, lipids, vitamin C. 03 recipe extracts at doses (75/25),(50/50),(25/75) were evaluated for antioxidant activity; the extract with faster healing properties was (75/25)..
Conclusion: Results obtained allowed us to develop monographs of plants, for our contribution to the future Cameroonian pharmacopoeia. In addition, the phytochemical and pharmacological study demonstrated the presence of biological markers responsible for the healing activity of recipe. The extract (75/25) was more effective. We can affirm in view of the results obtained that standardization is keen to promote traditional medicine.

Audience Take Away: 

• The importance of standardization of traditional recipes to discover new therapeuticals
• The development of innovative means to standardize recipes 
• Standardization leads to adequate results for valorization of traditional medicine

Biography:

Dr. NGONO MBALLA Rose, studied pharmacy at Marseille Mediterranean Faculty of Pharmacy, France and graduated as PharmD In 1988. She joined the Ministry of Research at IMPM from 1989 to 1993; and graduated as 3rdCycle Dr. in Biochemistry at 1993, Yaoundé 1 University. After she become Director of Pharmaceutical Services, (1995 to 1998). Then she worked as Temporary Adviser in WHOAFRO (1999-2000); Technical Officer in WHO Geneva (2001); WHO National Officer in Cameroon Country office (2002-2011). She came back to academic as Lecturer (2012-2016), Senior Lecturer (2017-2022); she received her PhD degree in 2021 at UY1. Meanwhile, she is Chair of the department of Pharmacology and Traditional Medicine since 2017, and DG LANACOME from 2015 to now. Associate Professor by January 2023, she has published more than 30 research articles and books.