HYBRID EVENT: You can participate in person at Valencia, Spain or Virtually from your home or work.
Hybrid Event
September 18-20, 2023 | Valencia, Spain
ICTM 2021

Ratchuporn Suksathan

Ratchuporn Suksathan, Speaker at Traditional Medicine Conferences
he Botanical Garden Organisation, Thailand
Title : In-vitro Anti-acetylcholinesterase inhibition and antioxidants of ginger plants

Abstract:

In this research, 5 plant species in family Zingiberaceae were initially analysed for phytochemicals, total phenolic contents (TPC), total flavonoid contents (TFC), antioxidant properties, as well as their anti-acetylcholinesterase inhibition. Alpinia nigra, Amomum biflorum, Amomum koenigii, Boesenbergia maxwellii and Etlingera araneosa were collected from Queen Sirikit Botanic Garden (QSBG) living collection in Thailand. The ethanol rhizome extracts gave percent yield ranged from 3.81-7.00 % (w/w). The results of anti-acetylcholinesterase inhibition of ginger plants are expressed with IC50 in ranged of 1.49- 4.94 mg/ mL. A. koenigii gave the best results of anti-oxidative property by 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assay, anti-acetylcholinesterase, percent yield, TPC and TFC. While A. biflorum showed the best antioxidant value with IC50 1.63 ± 0.02 by 2,2-diphenyl-1-picrylhydrazyl (DPPH). The chemical constituents of ethanol rhizome extracts were also characterised using High Performance Thin Layer Chromatography (HPTLC) and Thin Layer Chromatography/ Compact Mass Spectrometer (TLC/ CMS), while the quantitative analyses of their chemical compounds were analysed by HPLC compared to standards (i.e., gallic acid, caffeic acid, vanillin, quercetin, luteolin and cyanidin chloride). The most active extracts showed the presence of phenolic and flavonoid compounds, these characteristics may be related with strong anti-Alzheimer and antioxidants.

Biography:

Dr. Ratchuporn Suksathan studied Pharmaceutical Science at the faculty of Pharmacy, Chiang Mai University, Thailand and graduated as MS in Botany from faculty of science in the same university. She is a researcher of Research and Product Development Section, Queen Sirikit Botanic Garden, Chiang Mai, Thailand. Her research interests include phytochemistry, aromatic plants, biological activities and natural products. She has published more than 17 research articles in SCI(E) journals. She is the inventor on at least 7 granted Thai petty patents involved in natural products.

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