Abstract:
Background: In patients with hyperglycemia, the resistance to oral antihyperglycemic drugs may lead to insulin therapy. Insulin therapy has some limitations, such as the cost of medicine, dose monitoring, and the risk of hypoglycemia. The classical text of Ayurveda has described several formulations for treating diabetes. The role of Ayurveda antidiabetic formulations needs to be studied for controlling hyperglycemia and reducing the dose and frequency of insulin administration. Vijayasaradi capsule is an antidiabetic herbal formulation mainly utilized to treat hyperglycemia.
Objective: This study aimed to evaluate the clinical efficacy of Vijayasaradi capsule as add-on management in the cases of insulin-dependent type 2 diabetes.
Materials and Methods: Seventy-nine patients of either sex with insulin-dependent diabetes mellitus (T2-IDDM) between 18 and 70 years were studied. The intervention for the control group (n=38) was hypoglycemic drugs with insulin injections. The trial group (n=41) was treated with the Vijayasaradi capsule, two capsules (500mg each) thrice daily before food, hypoglycemic medicine, and insulin injection. The duration of the study was 3 months, and follow-ups were done weekly. Percentage changes of reduction in the units of insulin therapy, fasting and postprandial blood sugar levels, and haemoglobin A1c before and after the treatment and the associated subjective symptoms of type 2 diabetes were the primary outcome measures.
Results: The trial drug significantly decreased fasting blood sugar (P=0.02) and postprandial blood sugar (P=0.0001). The average insulin dose was also reduced from 33.27±19 to 28.8±80 units. A significant reduction (P=0.001) in haemoglobin A1c was observed after the treatment. After the treatment, reduction in the maximum average insulin dose was also observed.
Conclusion: Vijaysaradi capsule can be used as an add-on therapy to manage hyperglycemia and reduce insulin doses in patients with T2-IDDM.
Biography:
Dr Jitendra have been awarded with 13 prestigious awards from the different plateform including ministry of AYUSH, MOHFW, CCRAS and Nongovernment organizations. Dr Jitendrakumar N Varsakiya is presently working as an Assistant Professor Postgraduate Department of Kayachikitsa, Chaudhary Brahm Prakash Ayurveda Charak Samsthan (An Autonomous body under the Govt. of NCT, New Delhi) with other additional charges i.e warden boys hostel, Social media champion, Nodal officer Ayusman Bharat Digital mission CBPACS, Nodal officer Website. He was born on 12th September 1989 in Jamnagar, Gujarat, India. He completed his B.A.M.S. in 2011 and M.D.(Ayu.) in Kayachikitsa (Internal medicine) in 2015 & PhD in 2018 from Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat under the guidance of Dr. Mandip Goyal, Dean of International studies, head and Professor, department of Kayachikitsa, ITRA, National Importanc of Ayurveda, Jamnagar, Gujarat, India. His area of specialization is Medicine-Kayachikitsa-mainly Vajeekarana (aphrodisiac therapy in Ayurveda) which includes mainly Male infertility and sexual issues and its related disorders. More than 1000 couples are able to achieve parenthood under the treatment of him. Till date approx. 5,00,000 patients taken the treatment of doctor at government organizations where he worked or working. In the field of infertility more than 1000 patients of male infertility treated by Dr Jitendra among all have healthy Childs at present, Scientific documentation and publications for the same is available online. He has also worked on different other aspects of clinical research like completed about 3000 procedures of Panchkarma {Virechana Karma (bio-purification therapy)} in different patients and cure their diseases by the Ayurveda. Among them Paralysis, Thyroid disorders, Obesity, Metabolic disorders, Skin disorders includes psoriasis, eczema are main, liver disease includes liver abscess, cirrhosis of liver, fatty liver, Hepatitis-B, carcinoma of liver, pitutory adenoma are main, digestive chronic disease like ulcerative colitis, crohn’s disease are, PCOD Alopecia aerate. More than 1000 diabetic patients cured with the Ayurveda treatments, more than 1500 patients treated of hypertension with pure Ayurveda treatments. He has put his sincere efforts to bring out this ancient knowledge of health promotion and diseases prevention and disseminated the same through different scientific publications. Dr. Jitendrakumar N Varsakiya has published more than 100 scientific research papers in Various National and International peer reviewed research journals. Also he had written three books on Male Infertility. He has also participated in CME programs, information technology training for AYUSH professionals at CDAC, participated in more than 150 State level, National and International Seminars & Workshops and has presented around 50 scientific papers among them 3 paper got the 1st prize as best oral paper presentation. He is also member of institutional Newsletter-editorial Board, deputed as institutional website manager, reviewer of more than 15 scientific journals indexed and pub med journals, investigator and co-coordinator of research projects held by CCRAS GOI India. He has also delivered guest lectures and talks in public awareness program mainly in National channel DD Bharati and Akashwani Bhavan New Delhi. He has given services as physician more than 20 medical camps in different villages of Gujarat during his post-graduation. Dr. Jitendra Visited the two contries for the officically Nepal and Dubai as an Ayurveda Expert to propogate the Ayurveda Knowledge globally sponsored by the Ministry of Ayush, GOI , New Delhi, India.
