Title : Application of traditional chinese medicine in the treatment and prevention of chronic bronchitis with obstructive emphysema
Abstract:
Objective: To investigate the therapeutic effect of traditional Chinese medicine on chronic bronchitis with obstructive emphysema.
Methods: 120 patients with chronic bronchitis with obstructive emphysema admitted to our hospital from March 2023 to March 2024 were selected and divided into control group and observation group according to random number table method, with 60 cases in each group. The control group was given conventional western medicine treatment, and the observation group was given conventional western medicine plus traditional Chinese medicine treatment. The pulmonary function indexes [forced expiratory volume in the first second (FEV1) and the ratio of FEV1 to total forced expiratory volume (FEV1/FVC)], TCM syndrome score, inflammatory factor levels [serum C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) and interleukin-6] of the two groups were compared before and after treatment (IL-6)] and microcirculation indicators [microvascular blood flow index (MFI), perfusion vessel ratio (PPV)].
Results? After treatment, the total effective rate was 93.54% in the treatment group and 71.87% in the observation group, and the difference between the two groups was statistically significant (P<0.05). After treatment, TCM syndrome scores in both groups decreased compared with those before treatment (P<0.05), and TCM syndrome scores in observation group were lower than those in control group (P<0.05). After treatment, the levels of FEV1 and FEV1/FVC in 2 groups were higher than those before treatment (P<0.05), and the two indexes in observation group were higher than those in control group (P<0.05). After treatment, the serum levels of CRP, TNF-α and IL-6 in 2 groups were lower than before treatment (P<0.05), and the levels of 3 inflammatory factors in observation group were lower than those in control group (P<0.05). After treatment, the levels of serum MPI and PPV in the 2 groups were lower than those before treatment (P<0.05), and the 2 indexes in the observation group were lower than those in the control group (P<0.05).
Conclusion: Traditional Chinese medicine is effective in the prevention and treatment of chronic bronchitis with obstructive emphysema, which can obviously improve clinical symptoms, inhibit inflammation, improve lung function and microcirculation function.
